4-Trimethylsilylaniline(CAS: 17889-23-5)

4-Trimethylsilylaniline (CAS: 17889-23-5) is a colorless to white crystalline solid. Its molecular weight is approximately 184.24 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. Chemically, it is a stable compound, but it can undergo silylation reactions under basic conditions.

4-Trimethylsilylaniline is typically synthesized by silylation of aniline with trimethylsilyl chloride in the presence of a base such as triethylamine. The reaction is carried out at room temperature and yields a product with high selectivity and good yield.

4-Trimethylsilylaniline (CAS: 17889-23-5) is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also used in the semiconductor industry for the production of photoresists and as a dopant in some applications. Additionally, it has applications in the preparation of materials for sensors and other specialized polymers.

When handling 4-Trimethylsilylaniline (CAS: 17889-23-5), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be handled using appropriate absorbents and disposed of according to local regulations. A Safety Data Sheet (SDS) should always be consulted for detailed handling instructions.