Peptide histidine isoleucine(CAS: 96849-38-6)

Peptide histidine isoleucine (CAS: 96849-38-6) is an amphoteric peptide. It has a molecular weight of approximately 332.4 Da and a pI of 7.6. This compound is soluble in water and slightly soluble in organic solvents. It shows moderate reactivity towards nucleophiles and electrophiles, making it useful in peptide synthesis and biological studies.

Peptide histidine isoleucine (CAS: 96849-38-6) is synthesized via solid-phase peptide synthesis (SPPS) using Fmoc chemistry. Commonly, the Fmoc-histidine and Fmoc-isoleucine building blocks are coupled sequentially on a solid support, followed by deprotection and cleavage from the support. Catalytic amounts of HOBt and DIC are used to enhance coupling efficiency and reduce side products.

Peptide histidine isoleucine (CAS: 96849-38-6) is primarily used in the pharmaceutical and biotechnology industries. It is employed in drug discovery, as a component of peptide libraries, and for the development of therapeutic peptides. This compound also finds applications in the polymer industry as a functional monomer and in sensor technology for specific molecular recognition.

When handling Peptide histidine isoleucine (CAS: 96849-38-6), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up using appropriate absorbents, and the area should be thoroughly washed down. Always refer to the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.