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2'-O-tert-Butyldimethylsilyluridine(CAS: 54925-71-2)
CAS Number
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Basic Information
Molecular Formula
C15H26N2O6Si
Molecular Weight
358.47 g/mol
Physical Properties
Melting Point
192-194 ºC (ethyl acetate hexane )
Density
1.25±0.1 g/cm3 (20 ºC 760 Torr),
Chemical Identifiers
SMILES
OC[C@@H]1[C@H]([C@H]([C@H](N2C(NC(C=C2)=O)=O)O1)O[Si](C)(C(C)(C)C)C)O
InChIKey
AYQZFVZTNUOLCQ-OJAKKHQRSA-N
Database References
MDL Number
MFCD28016405
FAQ
2'-O-tert-Butyldimethylsilyluridine is a modified nucleoside commonly used in chemical synthesis and pharmaceutical research. It consists of a uracil base linked to a 2'-position ribose sugar, with a tert-butyldimethylsilyl group attached at the 2' position.
2'-O-tert-Butyldimethylsilyluridine is primarily used in the synthesis of nucleoside analogs for antiviral and anticancer drugs. It is also utilized in research to protect the ribose from hydrolysis, facilitating the study of nucleic acid chemistry and structure.
2'-O-tert-Butyldimethylsilyluridine is generally safe when handled with appropriate protective measures. However, it should be used with caution, as it can cause skin irritation. Proper handling, including the use of gloves and goggles, is recommended.
2'-O-tert-Butyldimethylsilyluridine should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent degradation. Optimal storage conditions include a temperature between 10°C and 25°C and a relative humidity below 60%.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
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