4-Amino-3-fluorophenol hydrochloride (1:1)(CAS: 18266-53-0)

4-Amino-3-fluorophenol hydrochloride (CAS: 18266-53-0) is a crystalline solid with a molecular weight of approximately 214.65 g/mol. It is slightly soluble in water and ethanol. This compound is known to be reactive towards bases and reducing agents. It is often used as an intermediate in pharmaceutical and chemical synthesis due to its chemical reactivity and functionality.

4-Amino-3-fluorophenol hydrochloride (CAS: 18266-53-0) can be synthesized through a two-step process. First, 3-fluoroaniline is treated with hydrochloric acid to form the hydrochloride salt. Then, the 4-amino group is introduced by amination using an appropriate amine under basic conditions. This process typically yields a product with good selectivity and high purity.

4-Amino-3-fluorophenol hydrochloride (CAS: 18266-53-0) is primarily used in the pharmaceutical industry for the synthesis of various bioactive compounds. It also has applications in the polymer industry for its reactive functionalities, and in the sensor industry due to its reactivity and ease of functionalization. Additionally, it can be used in semiconductor applications for certain organic electronic devices.

When handling 4-Amino-3-fluorophenol hydrochloride (CAS: 18266-53-0), appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat should be worn. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation. Spills should be contained and cleaned up using appropriate absorbents, and the area should be adequately rinsed. The material safety data sheet (MSDS) should always be referenced for detailed safety information.