Compound Q&A

How is 4-Amino-3-fluorophenol hydrochloride (CAS: 18266-53-0) typically synthesized?

Answer

4-Amino-3-fluorophenol hydrochloride (1:1)
4-Amino-3-fluorophenol hydrochloride (CAS: 18266-53-0) can be synthesized through a two-step process. First, 3-fluoroaniline is treated with hydrochloric acid to form the hydrochloride salt. Then, the 4-amino group is introduced by amination using an appropriate amine under basic conditions. This process typically yields a product with good selectivity and high purity.

About

CAS No 18266-53-0
English Name 4-Amino-3-fluorophenol hydrochloride (1:1)
Molecular Formula C6H7ClFNO
Molecular Weight 163.58 g/mol
SMILES C1=CC(=C(C=C1O)F)N.Cl
InChIKey BUNOVSISSBLYTC-UHFFFAOYSA-N
Last Updated: 2025-11-01 22:12

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