3',5'-Di-O-benzoyl Fialuridine(CAS: 97614-45-4)

3',5'-Di-O-benzoyl Fialuridine is a crystalline compound with a molecular weight of approximately 546.4 g/mol. It has a low solubility in water and is soluble in organic solvents like methanol and acetone. The compound is relatively stable but can undergo hydrolysis in the presence of moisture. Its reactivity is moderate and mainly involves ester hydrolysis and benzoylation reactions.

3',5'-Di-O-benzoyl Fialuridine is typically synthesized through the benzoylation of fialuridine using benzoyl chloride and a base like sodium hydride. The reaction is conducted in an inert solvent such as tetrahydrofuran (THF) at room temperature. The yield is around 75-80% with high selectivity towards the desired product.

3',5'-Di-O-benzoyl Fialuridine is primarily used in the pharmaceutical industry as an intermediate for drug synthesis. It is also relevant in the polymer industry for preparing functional polymers with specific properties. Its applications in sensors and semiconductors are less common but have been explored for specialized purposes.

When handling 3',5'-Di-O-benzoyl Fialuridine, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and moisture. Fume hoods should be used during synthesis to minimize exposure to volatile organic compounds. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.