tert-Butyl n-[(1r,4r,5s)-2-azabicyclo[2.2.1]heptan-5-yl]carbamate(CAS: 1932203-04-7)

The compound tert-Butyl n-[(1r,4r,5s)-2-azabicyclo[2.2.1]heptan-5-yl]carbamate has a crystalline form and a molecular weight of approximately 229.3 g/mol. It is poorly soluble in water but soluble in organic solvents. Reactivity is moderate, with typical pKa values indicating basic properties. It is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.

tert-Butyl n-[(1r,4r,5s)-2-azabicyclo[2.2.1]heptan-5-yl]carbamate is typically synthesized via a multi-step reaction involving the formation of the azabicyclic ring followed by carbamoylation. Commonly, the reaction is catalyzed by a suitable amine acceptor, and the process yields up to 85% product purity with excellent regioselectivity. The reaction conditions are optimized for efficiency and yield.

tert-Butyl n-[(1r,4r,5s)-2-azabicyclo[2.2.1]heptan-5-yl]carbamate is utilized in pharmaceuticals for the synthesis of complex molecules and in polymer science for functionalizing polymers. It also finds applications in sensor technology and semiconductor industries for specific chemical modification purposes. Its unique structure makes it a valuable intermediate in various chemical processes.

When handling tert-Butyl n-[(1r,4r,5s)-2-azabicyclo[2.2.1]heptan-5-yl]carbamate, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place and handled in a well-ventilated area or fume hood to avoid inhalation. In case of spill, immediately clean up using appropriate methods and refer to the Material Safety Data Sheet (MSDS) for detailed information and emergency procedures.