2-Phenyl-4(1H)-quinazolinone(CAS: 1022-45-3)

2-Phenyl-4(1H)-quinazolinone (CAS: 1022-45-3) is a crystalline compound with a molecular weight of approximately 207.22 g/mol. It is soluble in common organic solvents like ethyl acetate and acetonitrile but has low solubility in water. This compound is relatively stable but can undergo thermal degradation. It reacts with various reagents such as acids and bases to form different products.

2-Phenyl-4(1H)-quinazolinone (CAS: 1022-45-3) can be synthesized by the condensation of 2-aminophenylacetic acid and benzaldehyde in the presence of a catalyst like p-toluenesulfonic acid. This method provides good yields and high selectivity. The product can also be obtained through the reduction of 2-phenyl-4(1H)-quinazolinone-3,4-dione.

2-Phenyl-4(1H)-quinazolinone (CAS: 1022-45-3) is used in the pharmaceutical industry for the development of potential antitumor agents. It also finds applications in the polymer industry for developing novel materials with specific properties. Additionally, it is utilized in the field of sensors and semiconductors due to its unique electronic and optical characteristics.

When handling 2-Phenyl-4(1H)-quinazolinone (CAS: 1022-45-3), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbents. Always consult a safety data sheet (SDS) for detailed safety information and emergency procedures.