4,4-Difluoro-1-methylpiperidine(CAS: 1186194-60-4)

4,4-Difluoro-1-methylpiperidine is a colorless liquid with a pungent odor. It has a molecular weight of approximately 142.04 g/mol. The compound is moderately soluble in water but soluble in organic solvents. Chemically, it is relatively stable but can react with strong bases and reducing agents.

4,4-Difluoro-1-methylpiperidine is synthesized via the reaction of 1-methylpiperidine with hydrogen fluoride (HF) in the presence of potassium fluoride (KF) as a catalyst. The process yields high purity material with a high selectivity and good yield.

4,4-Difluoro-1-methylpiperidine finds applications in the pharmaceutical industry as an intermediate for drug synthesis, in the polymer industry for its use in the preparation of functional polymers, and in the sensor industry for its role in gas sensing applications.

When handling 4,4-Difluoro-1-methylpiperidine, wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. It should be stored in a well-ventilated area, away from strong acids and bases. Spills should be handled carefully and cleaned up with appropriate absorbent materials. Always consult a Safety Data Sheet (SDS) for detailed safety information.