Methyl 5-bromo-2-hydroxy-3-nitrobenzoate(CAS: 91983-31-2)

Methyl 5-bromo-2-hydroxy-3-nitrobenzoate (CAS: 91983-31-2) is a crystalline solid with a molecular weight of approximately 322.04 g/mol. It has a solubility of about 0.15 g/L in water and is slightly soluble in common organic solvents. This compound is highly reactive, particularly towards nucleophiles and reducing agents. It is sensitive to light and air, leading to degradation and discoloration.

Methyl 5-bromo-2-hydroxy-3-nitrobenzoate is typically synthesized via the nitration of methyl 5-bromo-2-hydroxybenzoate in the presence of concentrated sulfuric acid as a catalyst. The reaction is carried out at a temperature around 50°C. The yield is generally around 70-80%, and the product is purified by recrystallization from ethanol.

Methyl 5-bromo-2-hydroxy-3-nitrobenzoate (CAS: 91983-31-2) is used in the pharmaceutical industry for the synthesis of certain intermediates and in the development of new drugs. It is also utilized in the production of various sensors, where its reactivity and specificity are advantageous. Additionally, it finds applications in the synthesis of materials for semiconductors and as a reagent in organic chemistry research.

When handling Methyl 5-bromo-2-hydroxy-3-nitrobenzoate (CAS: 91983-31-2), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood due to its sensitivity to light and air. Spills should be cleaned up immediately with appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for specific handling and disposal instructions.