Lixivaptan(CAS: 168079-32-1)

Lixivaptan (CAS: 168079-32-1) is a crystalline compound with a molecular weight of approximately 413.47 g/mol. It is sparingly soluble in water and more soluble in organic solvents like methanol and ethanol. Lixivaptan is known for its high reactivity towards acidic conditions, and it is stable under basic conditions.

Lixivaptan (CAS: 168079-32-1) is synthesized through a multi-step process involving the protection of a hydroxyl group, subsequent coupling, and deprotection. Commonly used catalysts include tetrakis(triphenylphosphine)palladium(0) and triethylamine. The overall yield is around 60-70%. The synthesis requires careful control of pH and temperature to ensure high selectivity and yield.

Lixivaptan (CAS: 168079-32-1) is primarily used in the pharmaceutical industry. It is a vasopressin receptor antagonist used in the treatment of hyponatremia. There are no significant uses in other industries such as polymers, sensors, or semiconductors.

Lixivaptan (CAS: 168079-32-1) should be handled with appropriate Personal Protective Equipment (PPE) including gloves, safety goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight. In case of a spill, it should be cleaned up immediately using appropriate absorbents. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.