Compound Q&A
How is Lixivaptan (CAS: 168079-32-1) typically synthesized?
Answer
Lixivaptan (CAS: 168079-32-1) is synthesized through a multi-step process involving the protection of a hydroxyl group, subsequent coupling, and deprotection. Commonly used catalysts include tetrakis(triphenylphosphine)palladium(0) and triethylamine. The overall yield is around 60-70%. The synthesis requires careful control of pH and temperature to ensure high selectivity and yield.
About
CAS No
168079-32-1
English Name
Lixivaptan
Molecular Formula
C27H21ClFN3O2
Molecular Weight
473.9 g/mol
SMILES
CC1=C(C=C(C=C1)F)C(=O)NC2=CC(=C(C=C2)C(=O)N3CC4=CC=CN4CC5=CC=CC=C53)Cl
InChIKey
PPHTXRNHTVLQED-UHFFFAOYSA-N
Last Updated: 2025-10-26 09:39
