Ethyl 2-piperidinecarboxylate hydrochloride (1:1)(CAS: 77034-33-4)

Ethyl 2-piperidinecarboxylate hydrochloride (CAS: 77034-33-4) is a crystalline solid with a molecular weight of approximately 195.7 g/mol. It has a pKa of around 1.6 and is soluble in water and ethanol. This compound is known for its reactivity towards nucleophiles and its ability to form salts with various cations. It is commonly used in organic synthesis and as a precursor in the pharmaceutical and polymer industries.

Ethyl 2-piperidinecarboxylate hydrochloride (CAS: 77034-33-4) can be synthesized by reacting piperidine with ethyl chloroacetate in the presence of a catalytic amount of a base like sodium bicarbonate. The reaction is typically carried out in an organic solvent such as methanol or ethanol, yielding the desired hydrochloride salt in high yield and good selectivity.

Ethyl 2-piperidinecarboxylate hydrochloride (CAS: 77034-33-4) is used in the pharmaceutical industry for the synthesis of certain drugs, in polymer production to enhance material properties, and in the development of sensors and semiconductors due to its chemical reactivity and ability to form stable derivatives.

When handling Ethyl 2-piperidinecarboxylate hydrochloride (CAS: 77034-33-4), appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. It should be stored in a cool, dry place away from direct sunlight and heat sources. In case of spills, they should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed information on safe handling and emergency procedures.