Compound Q&A
How is Ethyl 2-piperidinecarboxylate hydrochloride (CAS: 77034-33-4) typically synthesized?
Answer
Ethyl 2-piperidinecarboxylate hydrochloride (CAS: 77034-33-4) can be synthesized by reacting piperidine with ethyl chloroacetate in the presence of a catalytic amount of a base like sodium bicarbonate. The reaction is typically carried out in an organic solvent such as methanol or ethanol, yielding the desired hydrochloride salt in high yield and good selectivity.
About
CAS No
77034-33-4
English Name
Ethyl 2-piperidinecarboxylate hydrochloride (1:1)
Molecular Formula
C8H16ClNO2
Molecular Weight
193.67 g/mol
SMILES
CCOC(=O)C1CCCCN1.Cl
InChIKey
KGAWPIXNSIYQPC-UHFFFAOYSA-N
Last Updated: 2025-10-01 13:51
