Ethyl 2-amino-5-chloronicotinate(CAS: 169495-51-6)

Ethyl 2-amino-5-chloronicotinate (CAS: 169495-51-6) is a crystalline compound with a molecular weight of approximately 251.68 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and acetone. The compound is relatively stable under normal conditions but reacts with strong bases to form the corresponding salt. It's often used in the synthesis of pharmaceuticals and other chemical intermediates.

Ethyl 2-amino-5-chloronicotinate (CAS: 169495-51-6) is typically synthesized by the reaction of nicotinic acid with ethylamine in the presence of a catalyst such as anhydrous aluminum chloride. The reaction yields a mixture that is purified by recrystallization. The process involves the introduction of an amino group and a chlorine atom to the nicotinic acid structure.

Ethyl 2-amino-5-chloronicotinate (CAS: 169495-51-6) is primarily used in the pharmaceutical industry as a precursor for the synthesis of other compounds. It also finds application in the production of certain polymers, sensors, and as a chemical intermediate in the semiconductor industry.

When handling Ethyl 2-amino-5-chloronicotinate (CAS: 169495-51-6), it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Work should be conducted in a well-ventilated area or fume hood. Spills should be carefully managed using appropriate absorbent materials and the area should be cleaned thoroughly. Always refer to the Safety Data Sheet (SDS) for detailed information on handling, storage, and emergency procedures.