17-phenyl-trinor-PGF2alpha amide(CAS: 155205-89-3)

17-phenyl-trinor-PGF2alpha amide is a crystalline compound with a molecular weight of approximately 422.37 g/mol. It has a low solubility in water but is more soluble in organic solvents like hexane and ethanol. The compound is highly reactive and can undergo hydrolysis under basic conditions. It has a melting point around 160-162°C.

17-phenyl-trinor-PGF2alpha amide is synthesized through a series of reactions including a Wittig reaction, followed by an amide formation step. The key reaction involves the Wittig reagent derived from 17-phenyl-trinor-PGF2alpha. The synthesis typically requires mild conditions and the use of a Lewis acid catalyst. The overall yield can range from 60-70%, with high selectivity for the desired amide product.

17-phenyl-trinor-PGF2alpha amide is mainly used in the pharmaceutical industry for its potential as a precursor in the synthesis of bioactive compounds. It can also find applications in the polymer industry for its potential use in the development of advanced materials, although its specific applications in this field are limited.

When handling 17-phenyl-trinor-PGF2alpha amide, appropriate personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and sources of ignition. Fume hoods should be used when performing operations that may release the compound into the air. In case of a spill, the area should be thoroughly cleaned, and the material safety data sheet (MSDS) should be consulted for detailed spill procedures.