4-(3-Chlorophenyl)-1,3-thiazol-2-amine(CAS: 90533-23-6)

4-(3-Chlorophenyl)-1,3-thiazol-2-amine (CAS: 90533-23-6) is a crystalline solid with a molecular weight of approximately 220.69 g/mol. It has a moderate solubility in common organic solvents like DMSO and ethanol. The compound shows basic behavior, which can affect its reactivity. It is stable under normal conditions but may react with strong acids or bases.

4-(3-Chlorophenyl)-1,3-thiazol-2-amine can be synthesized through a multi-step process involving the coupling of 3-chlorophenyl isocyanate with thiosemicarbazide. The reaction typically requires an appropriate base and is conducted in solvents like DMF. The yield is generally high, but conditions must be carefully controlled to ensure selectivity.

4-(3-Chlorophenyl)-1,3-thiazol-2-amine is used in pharmaceuticals for its biological activity and potential as a drug candidate. It also finds applications in the synthesis of other complex molecules and in the development of sensors. While its use in semiconductors is less common, it may contribute to the development of new materials in this field.

When handling 4-(3-Chlorophenyl)-1,3-thiazol-2-amine (CAS: 90533-23-6), appropriate personal protective equipment (PPE) should be worn, including gloves and goggles. The compound should be stored in a cool, dry place away from direct sunlight. In case of spill, the area should be ventilated and the spill cleaned up using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed guidelines.