1-Fluoro-2-iodo-4-nitrobenzene(CAS: 177363-10-9)

1-Fluoro-2-iodo-4-nitrobenzene (CAS: 177363-10-9) is a crystalline solid with a molecular weight of approximately 293.01 g/mol. It has a low solubility in water but is more soluble in common organic solvents like dichloromethane and ethanol. The compound is known for its high reactivity due to the presence of multiple functional groups, making it susceptible to substitution and reduction reactions.

1-Fluoro-2-iodo-4-nitrobenzene (CAS: 177363-10-9) can be synthesized via a multistep process involving the iodination of 1-fluoro-4-nitrobenzene followed by nitration. Common reagents include iodine in the presence of base and nitric acid. The synthesis typically yields about 70-80% of the desired product with good selectivity for the 2-iodo position.

1-Fluoro-2-iodo-4-nitrobenzene (CAS: 177363-10-9) is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the production of organic semiconductors and as an intermediate in the development of sensors and polymers. Its unique functional groups make it valuable for a variety of applications in chemical research and development.

When handling 1-Fluoro-2-iodo-4-nitrobenzene (CAS: 177363-10-9), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight. In case of spill, use appropriate absorbent materials and clean up under a fume hood. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.