Estra-1,3,5(10)-triene-3,17-diol, 2-bromo-, (17β)-(CAS: 15833-07-5)

Estra-1,3,5(10)-triene-3,17-diol, 2-bromo-, (17β)- (CAS: 15833-07-5) is a crystalline compound with a molecular weight of approximately 359.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like methanol and ethanol. The compound is relatively stable but can react with bases to form salts. It is an important intermediate in steroid synthesis.

Estra-1,3,5(10)-triene-3,17-diol, 2-bromo-, (17β)- (CAS: 15833-07-5) is typically synthesized through bromination of estrane-1,3,5(10)-triene-3,17-diol, followed by catalytic hydrogenation. Common catalysts include palladium on carbon. The synthesis process typically yields approximately 85% of the desired product, with good selectivity towards the (17β) configuration.

Estra-1,3,5(10)-triene-3,17-diol, 2-bromo-, (17β)- (CAS: 15833-07-5) is primarily used in the pharmaceutical and steroid synthesis industries. It serves as a key intermediate in the production of various steroid hormones and related drugs. Additionally, it finds applications in the cosmetic and research industries.

When handling Estra-1,3,5(10)-triene-3,17-diol, 2-bromo-, (17β)- (CAS: 15833-07-5), always wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood. Spills should be immediately cleaned up using appropriate absorbent materials. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions. The compound is stable under normal storage conditions, but avoid ingestion or inhalation of fumes.