Compound Q&A

How is Estra-1,3,5(10)-triene-3,17-diol, 2-bromo-, (17β)- (CAS: 15833-07-5) typically synthesized?

Answer

Estra-1,3,5(10)-triene-3,17-diol, 2-bromo-, (17β)-
Estra-1,3,5(10)-triene-3,17-diol, 2-bromo-, (17β)- (CAS: 15833-07-5) is typically synthesized through bromination of estrane-1,3,5(10)-triene-3,17-diol, followed by catalytic hydrogenation. Common catalysts include palladium on carbon. The synthesis process typically yields approximately 85% of the desired product, with good selectivity towards the (17β) configuration.

About

CAS No 15833-07-5
English Name Estra-1,3,5(10)-triene-3,17-diol, 2-bromo-, (17β)-
Molecular Formula C18H23BrO2
Molecular Weight 351.28 g/mol
SMILES CC12CCC3C(C1CCC2O)CCC4=CC(=C(C=C34)Br)O
InChIKey SORISAYAZBCIQH-XSSYPUMDSA-N
Last Updated: 2025-10-28 15:15

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