2-{[(1S)-1-Phenylethyl]carbamoyl}benzoic acid(CAS: 21752-36-3)

2-{[(1S)-1-Phenylethyl]carbamoyl}benzoic acid is a solid with a crystalline form. Its molecular weight is approximately 289.31 g/mol. It has a melting point of 225-227°C and is slightly soluble in water. This compound exhibits moderate reactivity in acidic conditions. It is used in various applications due to its chemical stability and reactivity.

2-{[(1S)-1-Phenylethyl]carbamoyl}benzoic acid can be synthesized through a multi-step process involving the reaction of phenylacetic acid with phenylethyl isocyanate. Commonly, this involves the formation of the isocyanate followed by its reaction with benzoic acid to form the final product. The process typically yields about 75-85% purity with good selectivity.

2-{[(1S)-1-Phenylethyl]carbamoyl}benzoic acid is used in the pharmaceutical industry for the development of drug intermediates. It also finds applications in polymer science for modifying properties of polymers. Additionally, it is used in the production of sensors and in semiconductor manufacturing due to its chemical stability and reactivity.

When handling 2-{[(1S)-1-Phenylethyl]carbamoyl}benzoic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure that the work is conducted in a well-ventilated area or a fume hood. In case of a spill, immediately clean up using appropriate absorbents and follow proper waste disposal protocols. Always refer to the safety data sheet (SDS) for more detailed information on handling and storage.