(3-Amino-4-methylphenyl)methanol(CAS: 81863-45-8)

(3-Amino-4-methylphenyl)methanol is a crystalline solid with a molecular weight of approximately 172.23 g/mol. It has a high solubility in water and organic solvents. Chemically, it is reactive with acids, bases, and electrophiles. It exhibits good solubility in common organic solvents like ethanol and acetone but is slightly less soluble in water (approximately 1.0 g/100 mL at 20°C).

(3-Amino-4-methylphenyl)methanol is typically synthesized via the condensation of 2-methyl-4-aminophenol with formaldehyde using a phase transfer catalyst. The reaction is carried out in a solvent such as methanol, and the product is isolated by crystallization. The yield is typically around 85% to 90%, and the reaction is selective and efficient.

(3-Amino-4-methylphenyl)methanol finds applications in various industries. It is used as a precursor in the pharmaceutical industry for the synthesis of drugs, particularly those that require aromatic amino functionalities. It is also utilized in the polymer industry for modifying polymers and in the production of sensors and semiconductors due to its unique chemical properties.

Proper handling of (3-Amino-4-methylphenyl)methanol (CAS: 81863-45-8) requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be handled in a well-ventilated area or a fume hood due to its reactivity. Spills should be cleaned up with caution, using appropriate absorbents. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.