Compound Q&A

How is (3-Amino-4-methylphenyl)methanol (CAS: 81863-45-8) typically synthesized?

Answer

(3-Amino-4-methylphenyl)methanol
(3-Amino-4-methylphenyl)methanol is typically synthesized via the condensation of 2-methyl-4-aminophenol with formaldehyde using a phase transfer catalyst. The reaction is carried out in a solvent such as methanol, and the product is isolated by crystallization. The yield is typically around 85% to 90%, and the reaction is selective and efficient.

About

CAS No 81863-45-8
English Name (3-Amino-4-methylphenyl)methanol
Molecular Formula C8H11NO
Molecular Weight 137.18 g/mol
SMILES Cc1ccc(CO)cc1N
InChIKey BCQKYGYTOHXGLL-UHFFFAOYSA-N
Last Updated: 2025-11-05 07:29

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