Ethyl (4-hydroxy-3,5-diiodophenyl)acetate(CAS: 90917-49-0)

Ethyl (4-hydroxy-3,5-diiodophenyl)acetate (CAS: 90917-49-0) is a crystalline solid with a high molecular weight. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. This compound is known for its low reactivity and stability under normal conditions. It does not readily undergo typical organic transformations such as nucleophilic substitution or alkylation due to its bulky and stable iodine substituents.

Ethyl (4-hydroxy-3,5-diiodophenyl)acetate (CAS: 90917-49-0) can be synthesized via a multistep process involving the iodination of an aromatic ring, followed by acetylation of the hydroxy group. Commonly, the iodination step involves the use of iodine and a Lewis acid catalyst, such as aluminum triisopropoxide. The acetylation step is achieved using acetyl chloride in the presence of a base like pyridine. The overall yield and selectivity are dependent on the reaction conditions and catalysts used.

Ethyl (4-hydroxy-3,5-diiodophenyl)acetate (CAS: 90917-49-0) is primarily used in the pharmaceutical industry for the synthesis of advanced intermediates. It also finds applications in the production of certain organic pigments and dyes due to its color and stability. Additionally, this compound may be used in research and development for its unique chemical properties.

When handling Ethyl (4-hydroxy-3,5-diiodophenyl)acetate (CAS: 90917-49-0), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. This compound should be handled in a well-ventilated area or a fume hood to minimize exposure. In case of a spill, immediately contain it and clean up using appropriate chemical spill kits. Always refer to the Material Safety Data Sheet (MSDS) for detailed information on handling and emergency procedures.