How is Ethyl (4-hydroxy-3,5-diiodophenyl)acetate (CAS: 90917-49-0) typically synthesized?

Ethyl (4-hydroxy-3,5-diiodophenyl)acetate (CAS: 90917-49-0) can be synthesized via a multistep process involving the iodination of an aromatic ring, followed by acetylation of the hydroxy group. Commonly, the iodination step involves the use of iodine and a Lewis acid catalyst, such as aluminum triisopropoxide. The acetylation step is achieved using acetyl chloride in the presence of a base like pyridine. The overall yield and selectivity are dependent on the reaction conditions and catalysts used.