(2-Isopropoxy-4-pyridinyl)methanol(CAS: 754218-88-7)

The compound (2-Isopropoxy-4-pyridinyl)methanol (CAS: 754218-88-7) is a crystalline solid with a molecular weight of approximately 211.24 g/mol. It has a low solubility in water (0.05 g/100 mL at 20°C) but is more soluble in organic solvents like methanol, ethanol, and acetone. It exhibits basic properties due to the presence of a pyridine ring, making it susceptible to acidic conditions. This compound is highly reactive in the presence of strong bases and reducing agents.

Synthesis of (2-Isopropoxy-4-pyridinyl)methanol (CAS: 754218-88-7) is typically achieved through an alkylation reaction of 4-pyridinemethanol with isopropyl bromide in the presence of a base like sodium hydride. The reaction yields a mixture of products which can be purified via recrystallization. The reaction is carried out in an inert atmosphere to prevent decomposition and to enhance yield and selectivity.

The compound (2-Isopropoxy-4-pyridinyl)methanol (CAS: 754218-88-7) is utilized in the pharmaceutical industry for the synthesis of certain drug precursors. It is also used in the development of materials for sensors and semiconductors due to its electronic properties. Additionally, it finds applications in the polymer industry for modifying and enhancing material properties.

When handling (2-Isopropoxy-4-pyridinyl)methanol (CAS: 754218-88-7), it is crucial to wear personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of spillage, use appropriate absorbent materials and ensure proper disposal according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.