(2-Isopropoxy-4-pyridinyl)methanol | CAS No. 754218-88-7

(2-Isopropoxy-4-pyridinyl)methanol

Basic Information

CAS Number

754218-88-7

Molecular Formula

C9H13NO2

Molecular Weight

167.21 g/mol

AD

Basic Physical Properties

CC(C)OC1=NC=CC(=C1)CO

InChI

InChI=1S/C9H13NO2/c1-7(2)12-9-5-8(6-11)3-4-10-9/h3-5,7,11H,6H2,1-2H3

InChIKey

HYBALJMVPJTQQE-UHFFFAOYSA-N

LogP

1.3611

Topological Polar Surface Area

42.35 Ų

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

128

Synonyms & References

English

  • MFCD14606470
  • EN300-221946
  • SCHEMBL4018741
  • [2-(propan-2-yloxy)pyridin-4-yl]methanol
  • 754218-88-7
  • (2-propan-2-yloxypyridin-4-yl)methanol
  • SB84978
  • AS-43424
  • CS-0195621
  • (2-Isopropoxypyridin-4-yl)methanol
  • AKOS010506699
  • 4-Pyridinemethanol,2-(1-methylethoxy)-
  • 4-Pyridinemethanol,2-(1-methylethoxy)-(9CI)

MDL Number

MFCD14606470

FAQ

What are the physical and chemical properties of (2-Isopropoxy-4-pyridinyl)methanol (CAS: 754218-88-7)?

The compound (2-Isopropoxy-4-pyridinyl)methanol (CAS: 754218-88-7) is a crystalline solid with a molecular weight of approximately 211.24 g/mol. It has a low solubility in water (0.05 g/100 mL at 20°C) but is more soluble in organic solvents like methanol, ethanol, and acetone. It exhibits basic properties due to the presence of a pyridine ring, making it susceptible to acidic conditions. This compound is highly reactive in the presence of strong bases and reducing agents.

How is (2-Isopropoxy-4-pyridinyl)methanol (CAS: 754218-88-7) typically synthesized?

Synthesis of (2-Isopropoxy-4-pyridinyl)methanol (CAS: 754218-88-7) is typically achieved through an alkylation reaction of 4-pyridinemethanol with isopropyl bromide in the presence of a base like sodium hydride. The reaction yields a mixture of products which can be purified via recrystallization. The reaction is carried out in an inert atmosphere to prevent decomposition and to enhance yield and selectivity.

What industries use (2-Isopropoxy-4-pyridinyl)methanol (CAS: 754218-88-7)?

The compound (2-Isopropoxy-4-pyridinyl)methanol (CAS: 754218-88-7) is utilized in the pharmaceutical industry for the synthesis of certain drug precursors. It is also used in the development of materials for sensors and semiconductors due to its electronic properties. Additionally, it finds applications in the polymer industry for modifying and enhancing material properties.

What precautions should be taken when handling (2-Isopropoxy-4-pyridinyl)methanol (CAS: 754218-88-7)?

When handling (2-Isopropoxy-4-pyridinyl)methanol (CAS: 754218-88-7), it is crucial to wear personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of spillage, use appropriate absorbent materials and ensure proper disposal according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.

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