2-Amino-4-bromo-6-fluorobenzoic acid(CAS: 1312454-86-6)

2-Amino-4-bromo-6-fluorobenzoic acid (CAS: 1312454-86-6) is a crystalline solid with a molecular weight of approximately 275.03 g/mol. It is sparingly soluble in water but has good solubility in organic solvents like ethanol and acetonitrile. Chemically, it is moderately reactive, especially towards nucleophiles, which can lead to substitution reactions. It is stable under normal conditions but should be stored in a dry, cool place to avoid moisture-induced degradation.

2-Amino-4-bromo-6-fluorobenzoic acid (CAS: 1312454-86-6) is typically synthesized via a bromination and fluorination of benzoic acid followed by coupling with an amine. The reaction is carried out in the presence of a Lewis acid catalyst such as aluminum chloride. The yield is typically around 70-80%, and the product can be isolated by recrystallization from ethanol.

2-Amino-4-bromo-6-fluorobenzoic acid (CAS: 1312454-86-6) is used in various industries, particularly in pharmaceuticals for the synthesis of novel drug candidates. It also finds applications in the development of sensors and semiconductors, where its functional groups provide unique properties for material science and electronics.

When handling 2-Amino-4-bromo-6-fluorobenzoic acid (CAS: 1312454-86-6), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Handle in a well-ventilated area or fume hood to minimize exposure to vapors. Spills should be cleaned up using appropriate absorbents and the site decontaminated. Always consult the Safety Data Sheet (SDS) for specific handling and disposal instructions.