Compound Q&A
How is 2-Amino-4-bromo-6-fluorobenzoic acid (CAS: 1312454-86-6) typically synthesized?
Answer
2-Amino-4-bromo-6-fluorobenzoic acid (CAS: 1312454-86-6) is typically synthesized via a bromination and fluorination of benzoic acid followed by coupling with an amine. The reaction is carried out in the presence of a Lewis acid catalyst such as aluminum chloride. The yield is typically around 70-80%, and the product can be isolated by recrystallization from ethanol.
About
CAS No
1312454-86-6
English Name
2-Amino-4-bromo-6-fluorobenzoic acid
Molecular Formula
C7H5BrFNO2
Molecular Weight
234.02 g/mol
SMILES
Brc1cc(N)c(c(c1)F)C(=O)O
InChIKey
VWMWKITYXSGIIM-UHFFFAOYSA-N
Last Updated: 2026-03-07 15:41
