4-methyl-2-(2-nitrophenyl)oxazole(CAS: 951884-48-3)

4-methyl-2-(2-nitrophenyl)oxazole (CAS: 951884-48-3) is a crystalline compound with a molecular weight of approximately 212.08 g/mol. It has a low solubility in water but is more soluble in organic solvents such as ethanol and acetone. This compound is known for its moderate reactivity, particularly in electrophilic substitution reactions. It is stable under normal laboratory conditions but requires proper handling to avoid decomposition.

4-methyl-2-(2-nitrophenyl)oxazole (CAS: 951884-48-3) can be synthesized through a condensation reaction between 2-nitrobenzaldehyde and methyl isothiocyanate in the presence of a base such as potassium carbonate. The reaction is performed under mild conditions, and the product is typically isolated by recrystallization. This method ensures high yield and selectivity.

4-methyl-2-(2-nitrophenyl)oxazole (CAS: 951884-48-3) is used in a variety of industries. It is often employed in pharmaceuticals as a precursor for drug synthesis, in polymers for its unique chemical properties, and in sensors for its ability to detect specific analytes. Additionally, it has applications in the semiconductor industry due to its electronic properties.

When handling 4-methyl-2-(2-nitrophenyl)oxazole (CAS: 951884-48-3), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize the risk of inhalation. Spills should be cleaned up immediately using appropriate absorbents, and the area should be thoroughly washed down. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal.