2-Methyl-3-thiophenecarbaldehyde(CAS: 84815-20-3)

2-Methyl-3-thiophenecarbaldehyde (CAS: 84815-20-3) is a crystalline solid with a molecular weight of approximately 132.17 g/mol. It is slightly soluble in water but miscible with ethanol and acetone. This compound is used in analytical chemistry due to its reactivity with various reagents, particularly those involving nucleophilic aromatic substitution reactions.

2-Methyl-3-thiophenecarbaldehyde can be synthesized through the reaction of 2-methyl-3-thiophenecarboxylic acid with phosphorus trichloride in the presence of anhydrous zinc chloride as a catalyst. The yield is typically around 85-90%, and the process is carried out under anhydrous conditions to prevent hydrolysis.

2-Methyl-3-thiophenecarbaldehyde (CAS: 84815-20-3) is primarily used in the pharmaceutical industry for the synthesis of certain antibiotics and in the production of organic pigments. It also finds applications in the manufacturing of sensors and semiconductors due to its unique chemical properties.

When handling 2-Methyl-3-thiophenecarbaldehyde (CAS: 84815-20-3), it is essential to wear appropriate personal protective equipment (PPE), including safety goggles, gloves, and lab coat. Work should be conducted in a well-ventilated area or fume hood. In case of a spill, neutralize the compound with an appropriate neutralizer and clean up using a suitable absorbent material. Refer to the Safety Data Sheet (SDS) for detailed emergency response procedures.