2-Methyl-3-thiophenecarbaldehyde

Basic Information

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CAS Number

84815-20-3

Molecular Formula

C6H6OS

Molecular Weight

126.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

SMILES

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CC1=C(C=CS1)C=O

InChI

InChI=1S/C6H6OS/c1-5-6(4-7)2-3-8-5/h2-4H,1H3

InChIKey

NSYHYZOBGJOIMD-UHFFFAOYSA-N

LogP

1.86902

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

92.5

Synonyms & References

English

84815-20-3
EN300-101658
2-methylthiophene-3-carbaldehyde
PS-4448
Z1255365611
SCHEMBL645134
AT16762
2-Methylthiophene-3-carboxaldehyde
DTXSID10336160
AKOS015898742
Boc-(S)-3-Amino-3-(4-bromo-phenyl)-propionicacid
2-Methyl-3-formylthiophene
2-Methyl-thiophene-3-carbaldehyde
A851076
FT-0715749
MFCD09864856
AB53893
3-thiophenecarboxaldehyde, 2-methyl-
CS-0196257
3-Formyl-2-methylthiophene
methyl-3-thiophenec arboxald ehyde
2-Methylthiophene-3-carbaldehyde
2-METHYLTHIOPHENE-3-CARBOXALDEHYDE
2-methyl-3-thiophenecarbaldehyde
2-methyl-3-thiophenecarboxaldehyde
2-methyl-thiophene-3-carbaldehyde
3-thiophenecarboxaldehyde,2-methyl

MDL Number

MFCD09864856

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 2-Methyl-3-thiophenecarbaldehyde (CAS: 84815-20-3)?

2-Methyl-3-thiophenecarbaldehyde (CAS: 84815-20-3) is a crystalline solid with a molecular weight of approximately 132.17 g/mol. It is slightly soluble in water but miscible with ethanol and acetone. This compound is used in analytical chemistry due to its reactivity with various reagents, particularly those involving nucleophilic aromatic substitution reactions.

How is 2-Methyl-3-thiophenecarbaldehyde (CAS: 84815-20-3) typically synthesized?

2-Methyl-3-thiophenecarbaldehyde can be synthesized through the reaction of 2-methyl-3-thiophenecarboxylic acid with phosphorus trichloride in the presence of anhydrous zinc chloride as a catalyst. The yield is typically around 85-90%, and the process is carried out under anhydrous conditions to prevent hydrolysis.

What industries use 2-Methyl-3-thiophenecarbaldehyde (CAS: 84815-20-3)?

2-Methyl-3-thiophenecarbaldehyde (CAS: 84815-20-3) is primarily used in the pharmaceutical industry for the synthesis of certain antibiotics and in the production of organic pigments. It also finds applications in the manufacturing of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling 2-Methyl-3-thiophenecarbaldehyde (CAS: 84815-20-3)?

When handling 2-Methyl-3-thiophenecarbaldehyde (CAS: 84815-20-3), it is essential to wear appropriate personal protective equipment (PPE), including safety goggles, gloves, and lab coat. Work should be conducted in a well-ventilated area or fume hood. In case of a spill, neutralize the compound with an appropriate neutralizer and clean up using a suitable absorbent material. Refer to the Safety Data Sheet (SDS) for detailed emergency response procedures.