Proadrenomedullin (1-20) (human)(CAS: 150238-87-2)

Proadrenomedullin (1-20) (human) is a polypeptide with a molecular weight of approximately 2479.42 Da. It has a crystalline form that is stable under neutral conditions and is poorly soluble in water. The compound is reactive towards proteases, which can lead to degradation. It is typically stored dry at -20°C and dissolved in appropriate buffers for use in biochemical assays.

Proadrenomedullin (1-20) (human) is synthesized through solid-phase peptide synthesis using Fmoc chemistry. The synthesis involves stepwise coupling of amino acids and protection/deprotection of the growing peptide chain. Yield and selectivity are typically high, and the final product is purified using HPLC to ensure high purity.

Proadrenomedullin (1-20) (human) is primarily used in the pharmaceutical industry for its potential in cardiovascular and neurohormonal research. It also has applications in the development of diagnostic tools for cardiovascular diseases and as a research tool in molecular biology and biochemistry.

When handling Proadrenomedullin (1-20) (human), it is recommended to wear appropriate personal protective equipment (PPE) including gloves, lab coat, and goggles. The compound should be stored in a cool, dry place away from direct sunlight. Spills should be handled in a well-ventilated area using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.