ethyl 2-(4-bromo-2-formylphenoxy)acetate(CAS: 51336-47-1)

Ethyl 2-(4-bromo-2-formylphenoxy)acetate (CAS: 51336-47-1) is a crystalline solid with a molecular weight of approximately 349.96 g/mol. It has a low solubility in water but is more soluble in organic solvents like methanol and ethanol. This compound is highly reactive due to the presence of the formyl group and bromine substituent, making it prone to nucleophilic and electrophilic reactions.

Ethyl 2-(4-bromo-2-formylphenoxy)acetate is typically synthesized by the condensation of ethyl 2-(4-bromo-2-hydroxyphenoxy)acetate with formaldehyde in the presence of a strong acid catalyst such as sulfuric acid. The reaction is conducted under reflux conditions with a yield of around 85%. The reaction is selective and proceeds smoothly under mild conditions.

Ethyl 2-(4-bromo-2-formylphenoxy)acetate (CAS: 51336-47-1) is used in the pharmaceutical industry for the synthesis of certain organic compounds and intermediates. It is also utilized in the polymer industry for the modification of polymers, and in the chemical sensing sector for the development of new sensing materials. Additionally, it has potential applications in the semiconductor industry as a dopant.

When handling ethyl 2-(4-bromo-2-formylphenoxy)acetate (CAS: 51336-47-1), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be stored in a fume hood to minimize exposure. In case of a spill, it should be cleaned up immediately using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for specific handling and disposal guidelines.