5-Nitro-2-indanol(CAS: 16513-67-0)

5-Nitro-2-indanol (CAS: 16513-67-0) is a crystalline solid with a molecular weight of approximately 201.09 g/mol. It has a low solubility in water but is more soluble in organic solvents. It is moderately reactive, especially towards reducing agents and nitrites. The compound exhibits a characteristic absorption band in the UV-Vis spectrum around 290 nm, which can be used for identification purposes.

5-Nitro-2-indanol (CAS: 16513-67-0) can be synthesized by nitration of 2-indanol using concentrated nitric acid and sulfuric acid as a catalyst. The reaction is carried out at low temperatures to achieve good selectivity. The yield is typically around 70-80%, and the product can be isolated by recrystallization from a suitable solvent.

5-Nitro-2-indanol (CAS: 16513-67-0) is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. It also finds applications in the preparation of sensors and as a reagent in semiconductors. Additionally, it can be used in the preparation of certain polymers and materials for specific industrial applications.

When handling 5-Nitro-2-indanol (CAS: 16513-67-0), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or under a fume hood to minimize inhalation risk. Spills should be cleaned up using appropriate absorbents and waste should be disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.