5-Nitro-2-indanol

Basic Information

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CAS Number

16513-67-0

Molecular Formula

C9H9NO3

Molecular Weight

179.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Boiling Point

339.1°C at 760 mmHg

Density

1.406

Flash Point

152.5°C

Refractive Index

1.651

SMILES

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C1C(CC2=C1C=CC(=C2)[N+](=O)[O-])O

InChI

InChI=1S/C9H9NO3/c11-9-4-6-1-2-8(10(12)13)3-7(6)5-9/h1-3,9,11H,4-5H2

InChIKey

VAPGHIYRAUSHOH-UHFFFAOYSA-N

LogP

1.57750

Complexity

213

Synonyms & References

English

5-nitro-2,3-dihydro-1H-inden-2-ol
5-nitro-indan-2-ol
AKOS006295140
SB84989
AM803295
MFCD04038637
5-Nitroindane-2-ol
2-Hydroxy-5-nitroindane
SCHEMBL2728205
AS-62275
SY127120
CS-0038865
1H-Inden-2-ol, 2,3-dihydro-5-nitro-
DTXSID10395035
16513-67-0
VAPGHIYRAUSHOH-UHFFFAOYSA-N
FT-0733733
5-Nitro-2,3-dihydro-1H-inden-2-ol
1H-Inden-2-ol,2,3-dihydro-5-nitro-
2-HYDROXY-5-NITROINDANE
1H-Inden-2-ol,2,3-dihydro-5-nitro
5-Nitro-indan-2-ol

MDL Number

MFCD04038637

Customs Code

2906299090

FAQ

What are the physical and chemical properties of 5-Nitro-2-indanol (CAS: 16513-67-0)?

5-Nitro-2-indanol (CAS: 16513-67-0) is a crystalline solid with a molecular weight of approximately 201.09 g/mol. It has a low solubility in water but is more soluble in organic solvents. It is moderately reactive, especially towards reducing agents and nitrites. The compound exhibits a characteristic absorption band in the UV-Vis spectrum around 290 nm, which can be used for identification purposes.

How is 5-Nitro-2-indanol (CAS: 16513-67-0) typically synthesized?

5-Nitro-2-indanol (CAS: 16513-67-0) can be synthesized by nitration of 2-indanol using concentrated nitric acid and sulfuric acid as a catalyst. The reaction is carried out at low temperatures to achieve good selectivity. The yield is typically around 70-80%, and the product can be isolated by recrystallization from a suitable solvent.

What industries use 5-Nitro-2-indanol (CAS: 16513-67-0)?

5-Nitro-2-indanol (CAS: 16513-67-0) is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. It also finds applications in the preparation of sensors and as a reagent in semiconductors. Additionally, it can be used in the preparation of certain polymers and materials for specific industrial applications.

What precautions should be taken when handling 5-Nitro-2-indanol (CAS: 16513-67-0)?

When handling 5-Nitro-2-indanol (CAS: 16513-67-0), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or under a fume hood to minimize inhalation risk. Spills should be cleaned up using appropriate absorbents and waste should be disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.