4-Bromo-2,6-bis(2-methyl-2-propanyl)phenol(CAS: 1139-52-2)

4-Bromo-2,6-bis(2-methyl-2-propanyl)phenol (CAS: 1139-52-2) is a crystalline solid with a molecular weight of approximately 356.01 g/mol. It has a low water solubility, with a solubility of about 0.01 g/L. Chemically, it is relatively unreactive, showing limited reactivity towards common nucleophiles and electrophiles. It has a melting point of around 55-57°C and a boiling point of approximately 232-234°C. This compound is often used in organic synthesis and pharmaceutical applications.

4-Bromo-2,6-bis(2-methyl-2-propanyl)phenol is typically synthesized via a multi-step process. It involves the bromination of 2,6-bis(2-methyl-2-propanyl)phenol using bromine in the presence of a suitable base. The reaction is carried out under anhydrous conditions to minimize side reactions. This method provides good yield and selectivity, making it a common approach in academic and industrial settings.

4-Bromo-2,6-bis(2-methyl-2-propanyl)phenol (CAS: 1139-52-2) is utilized in various industries, particularly in pharmaceuticals, where it serves as a precursor for the synthesis of active pharmaceutical ingredients. It is also used in polymer chemistry for the modification of polymer properties and in semiconductor manufacturing for etching processes. Additionally, it plays a role in the development of chemical sensors due to its unique reactivity and stability.

When handling 4-Bromo-2,6-bis(2-methyl-2-propanyl)phenol (CAS: 1139-52-2), it is essential to follow safety protocols. Always wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Ensure the work area is well-ventilated and use a fume hood to minimize exposure. Spills should be cleaned up immediately using a suitable absorbent material. It is recommended to consult the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.