5-Chloro-4-fluoro-2-nitroaniline(CAS: 104222-34-6)

5-Chloro-4-fluoro-2-nitroaniline (CAS: 104222-34-6) is a crystalline solid with a molecular weight of 188.01 g/mol. It has a melting point of 168-169°C. The compound is only slightly soluble in water but soluble in organic solvents like ethanol and acetone. It shows good reactivity towards nucleophiles and electrophiles, making it a versatile intermediate in organic synthesis.

5-Chloro-4-fluoro-2-nitroaniline (CAS: 104222-34-6) can be synthesized through the nitration of 4-chloro-2-fluoroaniline with nitric acid in the presence of sulfuric acid as a catalyst. The reaction yields 5-Chloro-4-fluoro-2-nitroaniline with high selectivity and moderate to good yield, typically around 70-80%.

5-Chloro-4-fluoro-2-nitroaniline (CAS: 104222-34-6) is used in various industries including pharmaceuticals, where it serves as a precursor for the synthesis of certain drugs. It is also used in the production of dyes and pigments, as a component in organic electronics, and in the development of new materials for sensors and semiconductors.

5-Chloro-4-fluoro-2-nitroaniline (CAS: 104222-34-6) should be handled with caution due to its reactivity and potential for forming explosive compounds. Always perform operations in a well-ventilated fume hood and use appropriate personal protective equipment (PPE), such as gloves, goggles, and a lab coat. Store the compound in a cool, dry place away from sources of ignition and incompatible materials. Refer to the Material Safety Data Sheet (MSDS) for more detailed safety information.