2-Chloro-9-methyl-3H-purin-6(9H)-one(CAS: 36323-92-9)

2-Chloro-9-methyl-3H-purin-6(9H)-one (CAS: 36323-92-9) is a solid with a crystalline form. It has a molecular weight of approximately 218.01 g/mol. The compound is slightly soluble in water and highly soluble in organic solvents like ethanol and methanol. It exhibits moderate reactivity, especially under basic conditions, and is used in the synthesis of nucleosides and nucleotides.

2-Chloro-9-methyl-3H-purin-6(9H)-one (CAS: 36323-92-9) is typically synthesized through the condensation of 9-methyladenine with chloroacetic acid. This process is catalyzed by a Lewis acid such as aluminum chloride or boron trifluoride. The yield is moderate, and the selectivity is high, with minimal side products formed.

2-Chloro-9-methyl-3H-purin-6(9H)-one (CAS: 36323-92-9) is primarily used in the pharmaceutical industry for the synthesis of nucleosides and nucleotides, which are essential components in the development of antiviral and anticancer drugs. It is also utilized in the chemical industry for research and development purposes.

When handling 2-Chloro-9-methyl-3H-purin-6(9H)-one (CAS: 36323-92-9), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or within a fume hood. In case of a spill, it should be cleaned up immediately using appropriate materials. Always refer to the Safety Data Sheet (SDS) for detailed safety information and procedures.