Chloro(methyl)phenylsilane(CAS: 1631-82-9)

Chloro(methyl)phenylsilane (CAS: 1631-82-9) is a colorless liquid at room temperature. It has a molecular weight of approximately 170.19 g/mol and a density around 0.92 g/cm³. Solubility in water is low, and it is soluble in common organic solvents like ethanol and acetone. Chemically, it is highly reactive due to the presence of the chloro and methyl groups, which can undergo substitution reactions under certain conditions.

Chloro(methyl)phenylsilane can be synthesized through the reaction of chlorotriphenylsilane with methyl halide (e.g., methyl chloride or methyl bromide) in the presence of a base such as potassium tert-butoxide. The reaction is typically carried out in an inert solvent like toluene or hexane. The process yields high selectivity and good to excellent yield depending on the choice of reagents and conditions.

Chloro(methyl)phenylsilane (CAS: 1631-82-9) is used in various industries, including pharmaceuticals, where it serves as a starting material for the synthesis of certain drugs. In the polymer industry, it is used as a crosslinking agent. It is also employed in the production of sensors and semiconductors for its unique chemical properties and reactivity.

When handling Chloro(methyl)phenylsilane (CAS: 1631-82-9), it is crucial to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or under a fume hood to minimize exposure. Spills should be handled immediately using appropriate spill kits. Always consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.