Ethyl 5-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate(CAS: 851725-98-9)

Ethyl 5-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate (CAS: 851725-98-9) is a crystalline compound with a molecular weight of approximately 229.12 g/mol. It has a moderate solubility in common organic solvents like ethanol and acetone. Chemically, it is reactive towards nucleophiles and can undergo nucleophilic substitution reactions. It is not flammable but requires caution due to its reactivity.

Ethyl 5-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate (CAS: 851725-98-9) is typically synthesized through a condensation reaction of ethyl 1-methyl-1H-pyrazole-4-carboxylate with difluoroacetic anhydride. This process can be catalyzed by acetic acid, and the yield is generally high, around 85-90%.

Ethyl 5-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate (CAS: 851725-98-9) finds applications in the pharmaceutical and agrochemical industries. It is used as an intermediate in the synthesis of various bioactive compounds and agrochemicals. Additionally, it may have potential uses in sensor technology and as a precursor in polymer synthesis.

When handling Ethyl 5-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate (CAS: 851725-98-9), it is crucial to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to avoid inhaling the compound. Spills should be cleaned up promptly with appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.