Compound Q&A

How is Ethyl 5-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate (CAS: 851725-98-9) typically synthesized?

Answer

Ethyl 5-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate
Ethyl 5-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate (CAS: 851725-98-9) is typically synthesized through a condensation reaction of ethyl 1-methyl-1H-pyrazole-4-carboxylate with difluoroacetic anhydride. This process can be catalyzed by acetic acid, and the yield is generally high, around 85-90%.

About

English Name Ethyl 5-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate
Molecular Formula C8H10F2N2O2
Molecular Weight 204.18 g/mol
SMILES CCOC(=O)C1=C(N(N=C1)C)C(F)F
InChIKey AYCXDJXKBPZTTR-UHFFFAOYSA-N
Last Updated: 2025-12-28 14:56

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