Adrenomedullin (AM) (13-52), human(CAS: 154765-05-6)

Adrenomedullin (AM) (13-52), human, is a 30-amino acid peptide with a molecular weight of approximately 3500 Da. It is highly soluble in water and less soluble in organic solvents. The compound is stable under neutral to slightly alkaline conditions but can be degraded under acidic conditions. It exhibits low reactivity with common reagents.

Adrenomedullin (AM) (13-52), human, is typically synthesized via solid-phase peptide synthesis (SPPS) using Fmoc chemistry. Commonly used protecting groups include Fmoc and Boc. The synthesis involves stepwise coupling of amino acids, followed by deprotection and purification, achieving a yield of around 70-80%.

Adrenomedullin (AM) (13-52), human, is primarily used in the pharmaceutical industry for research on cardiovascular diseases and hypertension. It is also utilized in biotechnology for developing peptide-based therapeutic agents. Additionally, it has potential applications in the diagnostic industry for creating biomarker assays.

When handling Adrenomedullin (AM) (13-52), human, ensure the use of personal protective equipment (PPE), including gloves, goggles, and lab coats. Work in a well-ventilated area, preferably with a fume hood. Store the compound at -20°C to -80°C to maintain stability. In case of a spill, use appropriate cleanup materials and follow laboratory safety protocols. Refer to the Safety Data Sheet (SDS) for detailed information and emergency procedures.