3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzoic acid(CAS: 391211-97-5)

3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzoic acid (CAS: 391211-97-5) is a white crystalline solid with a molecular weight of approximately 406.05 g/mol. It has a low solubility in water but is soluble in organic solvents like DMSO and acetonitrile. The compound is known for its high reactivity due to the presence of fluoro and iodo substituents, making it prone to nucleophilic and electrophilic reactions.

3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzoic acid (CAS: 391211-97-5) is typically synthesized via a multi-step process involving the reaction of an intermediate amine with 3,4-difluorobenzoic acid. Commonly used catalysts include palladium or rhodium complexes. The synthesis involves careful control of reaction conditions to achieve high yields and selectivity.

3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzoic acid (CAS: 391211-97-5) is primarily used in the pharmaceutical industry for the development of new drugs. It also finds applications in materials science, particularly in the synthesis of advanced polymers and as a component in sensors and semiconductors.

When handling 3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzoic acid (CAS: 391211-97-5), it is crucial to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be immediately cleaned up with appropriate absorbent material and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.