2-(4-Morpholinyl)-4H-benzo[h]chromen-4-one(CAS: 154447-35-5)

2-(4-Morpholinyl)-4H-benzo[h]chromen-4-one (CAS: 154447-35-5) is typically a white crystalline solid with a molecular weight of approximately 312.43 g/mol. It has limited water solubility and is soluble in organic solvents such as methanol and acetonitrile. The compound is relatively stable under normal conditions but can react with strong acids and bases. It exhibits significant UV absorption in the 250-350 nm range, which can be useful for analytical purposes.

2-(4-Morpholinyl)-4H-benzo[h]chromen-4-one can be synthesized through the condensation of 4-hydroxybenzaldehyde and morpholine, followed by dehydration. The reaction typically requires a strong acid catalyst like sulfuric acid. The yield is around 70-80%, and the method offers good selectivity for the desired product. Other routes include the use of more complex intermediates, which can increase the reaction complexity and yield.

2-(4-Morpholinyl)-4H-benzo[h]chromen-4-one is used in the pharmaceutical industry for the development of potential analgesic and anti-inflammatory drugs. In the polymer industry, it can be used as a monomer in the synthesis of certain polymers with specific optical properties. Additionally, it has applications in sensor technology and semiconductor manufacturing, where its chromophoric properties are utilized.

When handling 2-(4-Morpholinyl)-4H-benzo[h]chromen-4-one, it is essential to wear appropriate personal protective equipment (PPE), including gloves, lab coat, and safety goggles. It should be stored in a cool, dry place, away from direct sunlight and heat sources. In case of a spill, the area should be ventilated, and the spill should be carefully cleaned up using appropriate absorbents. For detailed information, refer to the Material Safety Data Sheet (MSDS).