Compound Q&A

How is 2-(4-Morpholinyl)-4H-benzo[h]chromen-4-one (CAS: 154447-35-5) typically synthesized?

Answer

2-(4-Morpholinyl)-4H-benzo[h]chromen-4-one
2-(4-Morpholinyl)-4H-benzo[h]chromen-4-one can be synthesized through the condensation of 4-hydroxybenzaldehyde and morpholine, followed by dehydration. The reaction typically requires a strong acid catalyst like sulfuric acid. The yield is around 70-80%, and the method offers good selectivity for the desired product. Other routes include the use of more complex intermediates, which can increase the reaction complexity and yield.

About

English Name 2-(4-Morpholinyl)-4H-benzo[h]chromen-4-one
Molecular Formula C17H15NO3
Molecular Weight 281.31 g/mol
SMILES O=c1cc(oc2c1ccc1c2cccc1)N1CCOCC1
InChIKey KKTZALUTXUZPSN-UHFFFAOYSA-N
Last Updated: 2025-10-16 16:48

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