2,4-Difluoro-5-nitrophenol(CAS: 113512-57-5)

CAS Number
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Basic Information
Molecular Formula
C6H3F2NO3
Molecular Weight
175.09 g/mol
Physical Properties
Melting Point
117-119 ºC
Boiling Point
160-162 ºC (24 Torr)
Flash Point
122.8±27.3 ºC,
Water Solubility
Sparingly soluble in water but readily soluble in organic solvents.
Chemical Identifiers
SMILES
Oc1cc([N+](=O)[O-])c(F)cc1F
InChIKey
SMRYCTJAGPDVEH-UHFFFAOYSA-N
Database References
MDL Number
MFCD08443942
FAQ
2,4-Difluoro-5-nitrophenol (CAS: 113512-57-5) is a crystalline solid with a molecular weight of 212.05 g/mol. It has a high solubility in organic solvents like dichloromethane and acetone. Chemically, it is highly reactive, showing reactivity towards nucleophiles and reducing agents. It is also unstable in strong bases and light exposure, leading to decomposition.
2,4-Difluoro-5-nitrophenol (CAS: 113512-57-5) is commonly synthesized via the nitration of 2,4-difluorophenol using concentrated nitric acid and sulfuric acid as the nitrating agent. The reaction is typically carried out under reflux conditions, and the product is purified by recrystallization. Catalysts like FeSO4 are often used to improve the selectivity and yield of the nitration step.
2,4-Difluoro-5-nitrophenol (CAS: 113512-57-5) is used in the pharmaceutical industry for the synthesis of certain drugs and intermediates. It is also used in the polymer industry for specialized applications and as a component in some organic synthesis reactions. Additionally, it finds use in the production of sensors and semiconductors due to its electronic properties.
When handling 2,4-Difluoro-5-nitrophenol (CAS: 113512-57-5), safety goggles and gloves must be worn. It should be stored in a cool, dry place away from direct sunlight and heat sources. Spills should be handled using personal protective equipment (PPE) and neutralized with an appropriate acid-base titration. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
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