Compound Q&A
How is 2,4-Difluoro-5-nitrophenol (CAS: 113512-57-5) typically synthesized?
Answer
2,4-Difluoro-5-nitrophenol (CAS: 113512-57-5) is commonly synthesized via the nitration of 2,4-difluorophenol using concentrated nitric acid and sulfuric acid as the nitrating agent. The reaction is typically carried out under reflux conditions, and the product is purified by recrystallization. Catalysts like FeSO4 are often used to improve the selectivity and yield of the nitration step.
About
CAS No
113512-57-5
English Name
2,4-Difluoro-5-nitrophenol
Molecular Formula
C6H3F2NO3
Molecular Weight
175.09 g/mol
SMILES
Oc1cc([N+](=O)[O-])c(F)cc1F
InChIKey
SMRYCTJAGPDVEH-UHFFFAOYSA-N
Last Updated: 2025-10-31 20:53
