Tert-butyl 4-iodobenzoate(CAS: 120363-13-5)

Tert-butyl 4-iodobenzoate (CAS: 120363-13-5) is a solid with a crystalline form. The molecular weight is approximately 320.02 g/mol. It has low water solubility but is soluble in organic solvents like dichloromethane and acetonitrile. Chemically, it is reactive towards nucleophiles and can undergo substitution reactions, making it useful in organic synthesis.

Tert-butyl 4-iodobenzoate (CAS: 120363-13-5) is typically synthesized through the reaction of 4-iodobenzoic acid with tert-butyl alcohol in the presence of a catalyst such as sulfuric acid or p-toluenesulfonic acid, followed by removal of the acid to yield the ester product with high yield and good selectivity.

Tert-butyl 4-iodobenzoate (CAS: 120363-13-5) finds applications in various industries, particularly in pharmaceuticals for producing intermediates, in polymer science for monomer synthesis, and in the synthesis of sensors and semiconductors as a key reagent due to its reactivity and specific functional groups.

When handling Tert-butyl 4-iodobenzoate (CAS: 120363-13-5), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be carried out in a fume hood to minimize inhalation risks. Spills should be cleaned up carefully following standard laboratory protocols. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.