4-(3-Methylphenyl)piperidine hydrochloride (1:1)(CAS: 80120-03-2)

4-(3-Methylphenyl)piperidine hydrochloride is a crystalline white powder with a molecular weight of approximately 236.3 g/mol. It has a low solubility in water but is soluble in organic solvents like methanol. This compound is less reactive under normal conditions but can undergo hydrolysis in basic solutions. It is commonly used in pharmaceutical applications and has a melting point around 170°C.

4-(3-Methylphenyl)piperidine hydrochloride is synthesized by treating 4-(3-methylphenyl)piperidine with hydrochloric acid. The reaction typically involves an esterification step followed by acid treatment to form the hydrochloride salt. Common solvents used include methanol, and the yield is usually around 85-90%. Catalysts such as sulfuric acid are often used to improve the reaction rate and selectivity.

4-(3-Methylphenyl)piperidine hydrochloride is primarily used in the pharmaceutical industry due to its potential as a drug component. It is also utilized in the chemical industry for the development of new materials and in research for its unique properties. Additionally, it has some applications in the polymer and sensor industries due to its functional group diversity and reactivity.

When handling 4-(3-Methylphenyl)piperidine hydrochloride, it is important to use appropriate personal protective equipment (PPE), including gloves and safety goggles. It should be stored in a cool, dry place and away from heat sources. If a spill occurs, it should be cleaned up using appropriate absorbent materials, and the area should be well ventilated. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and guidelines.